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Platelet count

LINC00649 · rs1034332

Where this position leads

Condition: Blood Cell Counts

rs1034332 Condition: Blood Cell Counts Blood Cell Counts Condition rs1034332 rs1034332 LINC00649

What the study found

Who was studied 721,201 African American or Afro-Caribbean, African ancestry, European ancestry, East Asian ancestry, Hispanic or Latin American and South Asian ancestry individuals.

The effect The reported allele is C; the catalogue records no effect size ; p = 7 × 10−24.

How common The C allele had a frequency of about 20% in the people studied.

Where it sits Chromosome 21, band 21q22.11 — in an intron of LINC00649.

What each result means

C/C Two copies of the version the research linked to Platelet count. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Platelet count. That is a smaller link than two copies.
T/T No copy of the version the research linked to Platelet count. This is the starting point the study compared everyone against.
Source

Questions about rs1034332

What is rs1034332?

rs1034332 is a single position in the genome, in or near the LINC00649 gene. Published research associates it with platelet count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1034332 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs1034332 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1034332 come from?

GWAS Catalog, Cell 2020, PMID:32888493. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Platelet count (rs1034332). MyGeneLog™. https://www.mygenelog.com/variants/rs1034332

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