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Who was studied 2,853 European ancestry cases and 37,405 European ancestry controls; replicated in 1,827 European ancestry cases and 2,181 European ancestry controls.
The effect
Each copy of the C allele carried 1.16 times the odds of Vitiligo (95% confidence interval 1.1-1.23); p = 3 × 10−8.
How common The C allele had a frequency of about 72% in the people studied.
Where it sits Chromosome 4, band 4q24 — in an intron of PPP3CA.
What each result means
A/ANo copy of the version the research linked to Vitiligo. This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to Vitiligo. That is a smaller link than two copies.
C/CTwo copies of the version the research linked to Vitiligo. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature genetics · 2016 · PMID 27723757 · open access
Questions about rs1031034
What is rs1031034?
rs1031034 is a single position in the genome, in or near the PPP3CA gene. Published research associates it with vitiligo. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1031034 linked to?
On MyGeneLog this position is linked to Vitiligo. The research behind each link, and its sources, are set out on that condition page.
Does having rs1031034 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1031034 come from?
GWAS Catalog, Nat Genet 2016, PMID:27723757. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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