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Male-pattern baldness

HDAC9 · rs10278449

Where this position leads

Condition: Androgenetic Alopecia (Male Pattern Baldness)

rs10278449 Condition: Androgenetic Alopecia (Male Pattern Baldness) Androgenetic Alopecia (Male Pattern… Condition rs10278449 rs10278449 HDAC9

What the study found

Who was studied 52,874 British ancestry males.

The effect Each copy of the T allele shifted the measure 0.0717 lower; p = 2 × 10−14.

Where it sits Chromosome 7, band 7p21.1 — in an intron of HDAC9.

What each result means

C/C No copy of the version the research linked to Male-pattern baldness. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Male-pattern baldness. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Male-pattern baldness. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10278449

What is rs10278449?

rs10278449 is a single position in the genome, in or near the HDAC9 gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10278449 linked to?

On MyGeneLog this position is linked to Androgenetic Alopecia (Male Pattern Baldness). The research behind each link, and its sources, are set out on that condition page.

Does having rs10278449 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10278449 come from?

GWAS Catalog, PLoS Genet 2017, PMID:28196072. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Male-pattern baldness (rs10278449). MyGeneLog™. https://www.mygenelog.com/variants/rs10278449

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