PHTF2 · rs10270542
Where this position leads
Condition: Kidney Function
What the study found
Who was studied 206,856 European ancestry individuals, 143,658 East Asian ancestry individuals.
The effect Each copy of the G allele shifted the measure 8.02 z score lower; p = 1 × 10−15.
How common The G allele had a frequency of about 33% in the people studied.
Where it sits Chromosome 7, band 7q11.23 — in an intron of PHTF2.
rs10270542 is a single position in the genome, in or near the PHTF2 gene. Published research associates it with estimated glomerular filtration rate. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Nat Commun 2019, PMID:31015462. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Estimated glomerular filtration rate (rs10270542). MyGeneLog™. https://www.mygenelog.com/variants/rs10270542