0 10127Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others7Total10Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 94,292 African American or Afro-Caribbean cases, 22,643 African American or Afro-Caribbean controls, 35,766 Hispanic or Latin American cases, 20,913 Hispanic or Latin American controls, 3,903 East Asian ancestry cases, 2,607 East Asian ancestry controls, 322,448 European ancestry cases, 105,690 European ancestry controls.
The effect
Each copy of the C allele shifted the measure 0.0476 lower (95% confidence interval 0.035-0.06); p = 2 × 10−12.
How common The C allele had a frequency of about 76% in the people studied.
Where it sits Chromosome 7, band 7q36.1 — in an intron of PRKAG2.
What each result means
C/CTwo copies of the version the research linked to Hypertension (PheCode 401). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Hypertension (PheCode 401). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Hypertension (PheCode 401). This is the starting point the study compared everyone against.
Science (New York, N.Y.) · 2024 · PMID 39024449 · open access
Questions about rs10253736
What is rs10253736?
rs10253736 is a single position in the genome, in or near the PRKAG2 gene. Published research associates it with hypertension (phecode 401). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10253736 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs10253736 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10253736 come from?
GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 10127Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others7Total10Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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