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Waist-to-hip ratio adjusted for body mass index

NFE2L3 · rs10245353

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Waist-to-hip ratio adjusted for body mass index compared to the general population. (GWAS Catalog, Nature 2015, PMID:25673412)
A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Waist-to-hip ratio adjusted for body mass index. (GWAS Catalog, Nature 2015, PMID:25673412)
C/C Published research associates this genotype with typical/baseline likelihood of Waist-to-hip ratio adjusted for body mass index — no copies of the reported risk allele. (GWAS Catalog, Nature 2015, PMID:25673412)
Source

Questions about rs10245353

What is rs10245353?

rs10245353 is a single position in the genome, in or near the NFE2L3 gene. Published research associates it with waist-to-hip ratio adjusted for body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10245353 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10245353 come from?

GWAS Catalog, Nature 2015, PMID:25673412. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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