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Depressive symptoms (MTAG)

near CTTNBP2 · rs10244364

Where this position leads

Condition: Depression (Self-Reported Symptoms)

rs10244364 Condition: Depression (Self-Reported Symptoms) Depression (Self-Reported Symptoms) Condition rs10244364 rs10244364 near CTTNBP2

What the study found

Who was studied 354,862 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0132 higher (95% confidence interval 0.0087-0.0177); p = 7 × 10−9.

How common The C allele had a frequency of about 32% in the people studied.

Where it sits Chromosome 7, band 7q31.31 — between genes, 15.4 kb from CTTNBP2.

What each result means

C/C Two copies of the version the research linked to Depressive symptoms (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Depressive symptoms (MTAG). That is a smaller link than two copies.
T/T No copy of the version the research linked to Depressive symptoms (MTAG). This is the starting point the study compared everyone against.
Source

Questions about rs10244364

What is rs10244364?

rs10244364 is a single position in the genome, in or near the near CTTNBP2 gene. Published research associates it with depressive symptoms (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10244364 linked to?

On MyGeneLog this position is linked to Depression (Self-Reported Symptoms). The research behind each link, and its sources, are set out on that condition page.

Does having rs10244364 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10244364 come from?

GWAS Catalog, Nat Genet 2018, PMID:29292387. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Depressive symptoms (MTAG) (rs10244364). MyGeneLog™. https://www.mygenelog.com/variants/rs10244364

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