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Carotid intima-media thickness (MTAG)

near TBX20 · rs10243790

What the study found

Who was studied at least 113,578 European ancestry individuals (MTAG boosted by 455,258 Alzheimer's disease samples).

The effect Each copy of the T allele shifted the measure 0.029 higher (95% confidence interval 0.019-0.039); p = 2 × 10−8.

Where it sits Chromosome 7, band 7p14.2 — between genes, 93 kb from TBX20.

What each result means

C/C No copy of the version the research linked to Carotid intima-media thickness (MTAG). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Carotid intima-media thickness (MTAG). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Carotid intima-media thickness (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10243790

What is rs10243790?

rs10243790 is a single position in the genome, in or near the near TBX20 gene. Published research associates it with carotid intima-media thickness (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10243790 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10243790 come from?

GWAS Catalog, Nature communications 2024, PMID:39537608. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Carotid intima-media thickness (MTAG) (rs10243790). MyGeneLog™. https://www.mygenelog.com/variants/rs10243790

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