Standard

Coriander liking

EXOC4 · rs10243750

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

Strength of the evidence

1 / 4

Its strongest genetic-study result is p = 10⁻⁸, with 1 associations in the GWAS Catalog.

How this is scored

4: ClinVar disease-causing, reviewed by an expert panel or a guideline (3–4 stars). 3: ClinVar, several labs agreeing (2 stars), or a genetic study at p ≤ 10⁻⁵⁰. 2: ClinVar from one lab (1 star), or p ≤ 10⁻²⁰. 1: ClinVar submitted without criteria (0 stars), or genome-wide significance (p ≤ 5×10⁻⁸). The higher of the two counts. It says how solid the evidence is, not whether it matters for a particular person.

What the study found

Who was studied 154,301 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0248 higher (95% confidence interval 0.017-0.033); p = 4 × 10⁻⁹.

How common The A allele had a frequency of about 24% in the people studied.

Where it sits Chromosome 7, band 7q33 — in an intron of EXOC4.

What each result means

A/A Two copies of the version the research linked to Coriander liking. That is the strongest link of the three results. A link in a study is not a diagnosis.

A/T One copy of the version the research linked to Coriander liking. That is a smaller link than two copies.

T/T No copy of the version the research linked to Coriander liking. This is the starting point the study compared everyone against.

Source

Large-scale GWAS of food liking reveals genetic determinants and genetic correlations with distinct neurophysiological traits

May-Wilson S, Matoba N, Wade KH, Hottenga JJ, Concas MP, Mangino M, Grzeszkowiak EJ, Menni C, Gasparini P, Timpson NJ, Veldhuizen MG, de Geus E

and 2 more — show all

Wilson JF, Pirastu N

Nature communications · 2022 · PMID 35585065 · open access

Questions about rs10243750

What is rs10243750?

rs10243750 is a single position in the genome, in or near the EXOC4 gene. Published research associates it with coriander liking. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10243750 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10243750 come from?

GWAS Catalog, Nature communications 2022, PMID:35585065. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Licensed CC BY-NC 4.0: free to read, share and adapt for non-commercial use, naming MyGeneLog™ and linking the exact page. Commercial use, including training or serving a commercial AI system, needs a licence — https://www.mygenelog.com/license

Coriander liking (rs10243750). MyGeneLog™. https://www.mygenelog.com/variants/rs10243750

← See all variants