A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Serum galactose-deficient IgA1 levels in IgA nephropathy compared to the general population. (GWAS Catalog, J Am Soc Nephrol 2021, PMID:33593824)
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Serum galactose-deficient IgA1 levels in IgA nephropathy. (GWAS Catalog, J Am Soc Nephrol 2021, PMID:33593824)
G/GPublished research associates this genotype with typical/baseline likelihood of Serum galactose-deficient IgA1 levels in IgA nephropathy — no copies of the reported risk allele. (GWAS Catalog, J Am Soc Nephrol 2021, PMID:33593824)
Source: GWAS Catalog, J Am Soc Nephrol 2021, PMID:33593824
Questions about rs10238682
What is rs10238682?
rs10238682 is a single position in the genome, in or near the C1GALT1 gene. Published research associates it with serum galactose-deficient iga1 levels in iga nephropathy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10238682 linked to?
On MyGeneLog this position is linked to IgA Nephropathy. The research behind each link, and its sources, are set out on that condition page.
Does having rs10238682 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10238682 come from?
GWAS Catalog, J Am Soc Nephrol 2021, PMID:33593824. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.