Standard

Cortical surface area

HDAC9 · rs10237280

What the study found

Who was studied 33,992 European ancestry individuals; replicated in 14,727 European ancestry individuals, 2,943 individuals.

The effect Each copy of the T allele shifted the measure 12.7 higher (95% confidence interval 9.22-16.24); p = 1 × 10−12.

How common The T allele had a frequency of about 39% in the people studied.

Where it sits Chromosome 7, band 7p21.1 — in an intron of HDAC9.

What each result means

C/C No copy of the version the research linked to Cortical surface area. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Cortical surface area. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Cortical surface area. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10237280

What is rs10237280?

rs10237280 is a single position in the genome, in or near the HDAC9 gene. Published research associates it with cortical surface area. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10237280 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10237280 come from?

GWAS Catalog, Science (New York, N.Y.) 2020, PMID:32193296. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Cortical surface area (rs10237280). MyGeneLog™. https://www.mygenelog.com/variants/rs10237280

← See all variants