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Gamma glutamyl transpeptidase

near CYP2W1 · rs10236293

Where this position leads

Condition: Colon Polyp

rs10236293 Condition: Colon Polyp Colon Polyp Condition rs10236293 rs10236293 near CYP2W1

What the study found

Who was studied 344,104 European ancestry individuals, 133,471 East Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0251 lower (95% confidence interval 0.021-0.03); p = 3 × 10−28.

Where it sits Chromosome 7, band 7p22.3 — between genes, 3.4 kb from CYP2W1.

What each result means

A/A Two copies of the version the research linked to Gamma glutamyl transpeptidase. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Gamma glutamyl transpeptidase. That is a smaller link than two copies.
G/G No copy of the version the research linked to Gamma glutamyl transpeptidase. This is the starting point the study compared everyone against.
Source

Questions about rs10236293

What is rs10236293?

rs10236293 is a single position in the genome, in or near the near CYP2W1 gene. Published research associates it with gamma glutamyl transpeptidase. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10236293 linked to?

On MyGeneLog this position is linked to Colon Polyp. The research behind each link, and its sources, are set out on that condition page.

Does having rs10236293 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10236293 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Gamma glutamyl transpeptidase (rs10236293). MyGeneLog™. https://www.mygenelog.com/variants/rs10236293

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