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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,121 European ancestry individuals; replicated in 499 European ancestry adolescent twins and siblings, 73 European ancestry adult individuals.
The effect
Each copy of the C allele shifted the measure 0.12 higher (95% confidence interval 0.08-0.16); p = 7 × 10−11.
Where it sits Chromosome 7, band 7q21.11 — in an intron of SEMA3A.
What each result means
C/CTwo copies of the version the research linked to Iris characteristics. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Iris characteristics. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Iris characteristics. This is the starting point the study compared everyone against.
American journal of human genetics · 2011 · PMID 21835309
Questions about rs10235789
What is rs10235789?
rs10235789 is a single position in the genome, in or near the SEMA3A gene. Published research associates it with iris characteristics. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10235789 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10235789 come from?
GWAS Catalog, American journal of human genetics 2011, PMID:21835309. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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