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Lobe size

MRPS22 · rs10212419

What the study found

Who was studied 4,919 Latin American individuals.

The effect Each copy of the A allele shifted the measure 0.107 higher; p = 3 × 10−14.

How common The A allele had a frequency of about 52% in the people studied.

Where it sits Chromosome 3, band 3q23 — in an intron of MRPS22.

What each result means

A/A Two copies of the version the research linked to Lobe size. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Lobe size. That is a smaller link than two copies.
G/G No copy of the version the research linked to Lobe size. This is the starting point the study compared everyone against.
Source

Questions about rs10212419

What is rs10212419?

rs10212419 is a single position in the genome, in or near the MRPS22 gene. Published research associates it with lobe size. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10212419 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10212419 come from?

GWAS Catalog, Nature communications 2015, PMID:26105758. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Lobe size (rs10212419). MyGeneLog™. https://www.mygenelog.com/variants/rs10212419

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