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Alanine levels

LINC02245 · rs10211524

What the study found

Who was studied 86,413 Caucasian ancestry individuals.

The effect Each copy of the G allele shifted the measure 10.7 (zscore) higher; p = 7 × 10−27.

How common The G allele had a frequency of about 58% in the people studied.

Where it sits Chromosome 2, band 2p14 — in an intron of LINC02245.

What each result means

A/A No copy of the version the research linked to Alanine levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Alanine levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Alanine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10211524

What is rs10211524?

rs10211524 is a single position in the genome, in or near the LINC02245 gene. Published research associates it with alanine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10211524 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10211524 come from?

GWAS Catalog, Nature genetics 2021, PMID:33414548. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Alanine levels (rs10211524). MyGeneLog™. https://www.mygenelog.com/variants/rs10211524

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