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Adult body size

CRIM1 · rs10204994

What the study found

Who was studied 453,169 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0101 higher (95% confidence interval 0.0069-0.0133); p = 5 × 10−10.

How common The G allele had a frequency of about 77% in the people studied.

Where it sits Chromosome 2, band 2p22.3 — between genes, 0.7 kb from SMIM7P1.

What each result means

A/A No copy of the version the research linked to Adult body size. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Adult body size. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Adult body size. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10204994

What is rs10204994?

rs10204994 is a single position in the genome, in or near the CRIM1 gene. Published research associates it with adult body size. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10204994 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10204994 come from?

GWAS Catalog, BMJ (Clinical research ed.) 2020, PMID:32376654. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Adult body size (rs10204994). MyGeneLog™. https://www.mygenelog.com/variants/rs10204994

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