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Who was studied 8,520 European ancestry cases, 479,981 European ancestry controls, 9,794 East Asian ancestry cases, 168,932 East Asian ancestry controls.
The effect
Each copy of the G allele shifted the measure 0.0666 lower (95% confidence interval 0.044-0.089); p = 8 × 10−9.
Where it sits Chromosome 2, band 2q24.3 — between genes, 27.7 kb from GALNT3.
What each result means
C/CNo copy of the version the research linked to Osteoporosis. This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Osteoporosis. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Osteoporosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs10204976 is a single position in the genome, in or near the near GALNT3 gene. Published research associates it with osteoporosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs10204976 linked to?
On MyGeneLog this position is linked to Osteoporosis. The research behind each link, and its sources, are set out on that condition page.
Does having rs10204976 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10204976 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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