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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,908 European ancestry cases, 436,579 European ancestry controls; replicated in 1,485 European ancestry cases, 137,185 European ancestry controls.
The effect
Each copy of the A allele shifted the measure 7.62 z score lower; p = 2 × 10−14.
Where it sits Chromosome 2, band 2q35 — in an intron of TESHL.
What each result means
A/ATwo copies of the version the research linked to Trigger finger. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Trigger finger. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Trigger finger. This is the starting point the study compared everyone against.
The Lancet. Rheumatology · 2022 · PMID 36043126 · open access
Questions about rs10203066
What is rs10203066?
rs10203066 is a single position in the genome, in or near the TESHL gene. Published research associates it with trigger finger. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10203066 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10203066 come from?
GWAS Catalog, The Lancet. Rheumatology 2022, PMID:36043126. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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