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Trans-laminar cribrosa pressure difference

TEX41 · rs10201197

What the study found

Who was studied 82,147 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.03 lower (95% confidence interval 0.02-0.04); p = 1 × 10−9.

How common The C allele had a frequency of about 34% in the people studied.

Where it sits Chromosome 2, band 2q22.3 — in an intron of TEX41.

What each result means

C/C Two copies of the version the research linked to Trans-laminar cribrosa pressure difference. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Trans-laminar cribrosa pressure difference. That is a smaller link than two copies.
T/T No copy of the version the research linked to Trans-laminar cribrosa pressure difference. This is the starting point the study compared everyone against.
Source

Questions about rs10201197

What is rs10201197?

rs10201197 is a single position in the genome, in or near the TEX41 gene. Published research associates it with trans-laminar cribrosa pressure difference. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10201197 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10201197 come from?

GWAS Catalog, Investigative ophthalmology & visual science 2026, PMID:42017308. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Trans-laminar cribrosa pressure difference (rs10201197). MyGeneLog™. https://www.mygenelog.com/variants/rs10201197

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