Standard

Triglycerides

near LINC01940 · rs10199914

Where this position leads

Condition: High Triglycerides

rs10199914 Condition: High Triglycerides High Triglycerides Condition rs10199914 rs10199914 near LINC019…

What the study found

Who was studied 215,551 European ancestry individuals, 57,332 African American individuals, 24,743 Hispanic individuals; replicated in Up to 319,677 individuals.

The effect Each copy of the A allele shifted the measure 0.0112 mg dl-1 lower (95% confidence interval 0.0075-0.0149); p = 4 × 10−9.

How common The A allele had a frequency of about 63% in the people studied.

Where it sits Chromosome 2, band 2q37.3 — between genes, 48.9 kb from LINC01940.

What each result means

A/A Two copies of the version the research linked to Triglycerides. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Triglycerides. That is a smaller link than two copies.
G/G No copy of the version the research linked to Triglycerides. This is the starting point the study compared everyone against.
Source

Questions about rs10199914

What is rs10199914?

rs10199914 is a single position in the genome, in or near the near LINC01940 gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10199914 linked to?

On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.

Does having rs10199914 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10199914 come from?

GWAS Catalog, Nature genetics 2018, PMID:30275531. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglycerides (rs10199914). MyGeneLog™. https://www.mygenelog.com/variants/rs10199914

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