Standard

Platelet count

RALB · rs10198758

Where this position leads

Condition: Blood Cell Counts

rs10198758 Condition: Blood Cell Counts Blood Cell Counts Condition rs10198758 rs10198758 RALB

What the study found

Who was studied 350,474 European ancestry individuals, 148,623 East Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0317 lower (95% confidence interval 0.027-0.037); p = 8 × 10−37.

Where it sits Chromosome 2, band 2q14.2 — in an intron of RALB.

What each result means

C/C Two copies of the version the research linked to Platelet count. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Platelet count. That is a smaller link than two copies.
T/T No copy of the version the research linked to Platelet count. This is the starting point the study compared everyone against.
Source

Questions about rs10198758

What is rs10198758?

rs10198758 is a single position in the genome, in or near the RALB gene. Published research associates it with platelet count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10198758 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs10198758 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10198758 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Platelet count (rs10198758). MyGeneLog™. https://www.mygenelog.com/variants/rs10198758

← See all variants