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Monocyte percentage of white cells

DOCK10 · rs10197805

Where this position leads

Condition: Blood Cell Counts

rs10197805 Condition: Blood Cell Counts Blood Cell Counts Condition rs10197805 rs10197805 DOCK10

What the study found

Who was studied 170,494 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0404 lower (95% confidence interval 0.031-0.05); p = 3 × 10−16.

How common The C allele had a frequency of about 16% in the people studied.

Where it sits Chromosome 2, band 2q36.2 — in an intron of DOCK10.

What each result means

C/C Two copies of the version the research linked to Monocyte percentage of white cells. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Monocyte percentage of white cells. That is a smaller link than two copies.
T/T No copy of the version the research linked to Monocyte percentage of white cells. This is the starting point the study compared everyone against.
Source

Questions about rs10197805

What is rs10197805?

rs10197805 is a single position in the genome, in or near the DOCK10 gene. Published research associates it with monocyte percentage of white cells. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10197805 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs10197805 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10197805 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Monocyte percentage of white cells (rs10197805). MyGeneLog™. https://www.mygenelog.com/variants/rs10197805

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