Sensitive

T-cell surface glycoprotein CD8 alpha chain level in Chronic kidney disease with hypertension and no diabetes (5992_50)

near CD8A · rs10197613

What the study found

Who was studied 466 African American individuals.

The effect Each copy of the C allele shifted the measure 0.84 lower (95% confidence interval 0.57-1.11); p = 4 × 10−12.

How common The C allele had a frequency of about 7% in the people studied.

Where it sits Chromosome 2, band 2p11.2 — between genes, 0.8 kb from CD8A.

What each result means

A/A No copy of the version the research linked to T-cell surface glycoprotein CD8 alpha chain level in Chronic kidney disease with hypertension and no diabetes (5992_50). This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to T-cell surface glycoprotein CD8 alpha chain level in Chronic kidney disease with hypertension and no diabetes (5992_50). That is a smaller link than two copies.
C/C Two copies of the version the research linked to T-cell surface glycoprotein CD8 alpha chain level in Chronic kidney disease with hypertension and no diabetes (5992_50). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10197613

What is rs10197613?

rs10197613 is a single position in the genome, in or near the near CD8A gene. Published research associates it with t-cell surface glycoprotein cd8 alpha chain level in chronic kidney disease with hypertension and no diabetes (5992_50). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10197613 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10197613 come from?

GWAS Catalog, Kidney international 2022, PMID:35870639. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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T-cell surface glycoprotein CD8 alpha chain level in Chronic kidney disease with hypertension and no diabetes (5992_50) (rs10197613). MyGeneLog™. https://www.mygenelog.com/variants/rs10197613

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