Standard

Mean corpuscular hemoglobin

ACOXL · rs10197140

Where this position leads

Condition: Blood Cell Counts

rs10197140 Condition: Blood Cell Counts Blood Cell Counts Condition rs10197140 rs10197140 ACOXL

What the study found

Who was studied 172,332 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0378 higher (95% confidence interval 0.03-0.045); p = 8 × 10−24.

How common The C allele had a frequency of about 34% in the people studied.

Where it sits Chromosome 2, band 2q13 — in an intron of ACOXL.

What each result means

C/C Two copies of the version the research linked to Mean corpuscular hemoglobin. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Mean corpuscular hemoglobin. That is a smaller link than two copies.
T/T No copy of the version the research linked to Mean corpuscular hemoglobin. This is the starting point the study compared everyone against.
Source

Questions about rs10197140

What is rs10197140?

rs10197140 is a single position in the genome, in or near the ACOXL gene. Published research associates it with mean corpuscular hemoglobin. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10197140 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs10197140 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10197140 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean corpuscular hemoglobin (rs10197140). MyGeneLog™. https://www.mygenelog.com/variants/rs10197140

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