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Cholesterol in very small VLDL (UKB data field 23519)

near APOB · rs10188514

What the study found

Who was studied 88,329 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.036 higher (95% confidence interval 0.027-0.045); p = 8 × 10−14.

How common The C allele had a frequency of about 36% in the people studied.

Where it sits Chromosome 2, band 2p24.1 — between genes, 67.1 kb from APOB.

What each result means

C/C Two copies of the version the research linked to Cholesterol in very small VLDL (UKB data field 23519). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Cholesterol in very small VLDL (UKB data field 23519). That is a smaller link than two copies.
T/T No copy of the version the research linked to Cholesterol in very small VLDL (UKB data field 23519). This is the starting point the study compared everyone against.
Source

Questions about rs10188514

What is rs10188514?

rs10188514 is a single position in the genome, in or near the near APOB gene. Published research associates it with cholesterol in very small vldl (ukb data field 23519). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10188514 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10188514 come from?

GWAS Catalog, Biological psychiatry 2023, PMID:36764567. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Cholesterol in very small VLDL (UKB data field 23519) (rs10188514). MyGeneLog™. https://www.mygenelog.com/variants/rs10188514

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