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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 2,466 Black/admixed ancestry individuals; replicated in up to 1,653 European, Hispanic, Asian or Black individuals.
The effect
Each copy of the C allele shifted the measure 0.36 higher (95% confidence interval 0.3-0.42); p = 4 × 10−31.
Where it sits Chromosome 2, band 2p23.3 — in an intron of KHK.
What each result means
C/CTwo copies of the version the research linked to Metabolite peak levels (QI4288). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Metabolite peak levels (QI4288). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Metabolite peak levels (QI4288). This is the starting point the study compared everyone against.
Nature communications · 2022 · PMID 35995766 · open access
Questions about rs10185736
What is rs10185736?
rs10185736 is a single position in the genome, in or near the KHK gene. Published research associates it with metabolite peak levels (qi4288). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10185736 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10185736 come from?
GWAS Catalog, Nature communications 2022, PMID:35995766. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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