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Prostate-specific antigen levels

GGCX · rs10172544

What the study found

Who was studied 61,745 African ancestry individuals, 6,967 Asian ancestry individuals, 297,166 European ancestry individuals, 26,644 Hispanic or Latin American individuals.

The effect Each copy of the A allele shifted the measure 0.0179 higher (95% confidence interval 0.014-0.021); p = 2 × 10−23.

Where it sits Chromosome 2, band 2p11.2 — in an intron of GGCX.

What ClinVar records

Classification Benign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 2 submitters), last evaluated 2018-07-09. ClinVar record 1183323 NM_000821.7(GGCX):c.44-162G>T

What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.

What each result means

A/A Two copies of the version the research linked to Prostate-specific antigen levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Prostate-specific antigen levels. That is a smaller link than two copies.
C/C No copy of the version the research linked to Prostate-specific antigen levels. This is the starting point the study compared everyone against.
Source

Questions about rs10172544

What is rs10172544?

rs10172544 is a single position in the genome, in or near the GGCX gene. Published research associates it with prostate-specific antigen levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10172544 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10172544 come from?

GWAS Catalog, Nature genetics 2025, PMID:39930085. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Prostate-specific antigen levels (rs10172544). MyGeneLog™. https://www.mygenelog.com/variants/rs10172544

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