Sensitive

Anxiety disorder

LINC01830 · rs10171148

Where this position leads

Condition: Anxiety Disorder

What the study found

Who was studied 1,096,458 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0125 lower; p = 1 × 10⁻⁹.

Where it sits Chromosome 2, band 2p24.1 — in an intron of LINC01830.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Anxiety disorder — no copies of the reported risk allele.

A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Anxiety disorder.

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Anxiety disorder compared to the general population.

Source

Gene discovery and biological insights into anxiety disorders from a large-scale multi-ancestry genome-wide association study

Friligkou E, Løkhammer S, Cabrera-Mendoza B, Shen J, He J, Deiana G, Zanoaga MD, Asgel Z, Pilcher A, Di Lascio L, Makharashvili A, Koller D

and 3 more — show all

Tylee DS, Pathak GA, Polimanti R

Nature genetics · 2024 · PMID 39294497

Questions about rs10171148

What is rs10171148?

rs10171148 is a single position in the genome, in or near the LINC01830 gene. Published research associates it with anxiety disorder. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10171148 linked to?

On MyGeneLog this position is linked to Anxiety Disorder. The research behind each link, and its sources, are set out on that condition page.

Does having rs10171148 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10171148 come from?

GWAS Catalog, Nature genetics 2024, PMID:39294497. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Anxiety disorder (rs10171148). MyGeneLog™. https://www.mygenelog.com/variants/rs10171148

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