0 1012223Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI2Microsoft · Copilot2Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total10Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 14,819 European ancestry cases, 941,863 European ancestry controls.
The effect
The reported allele is G; the catalogue records no effect size
; p = 1 × 10−14.
Where it sits Chromosome 1, band 1q24.2 — in an intron of PRRX1.
What each result means
C/CNo copy of the version the research linked to Calcific aortic valve stenosis. This is the starting point the study compared everyone against.
C/GOne copy of the version the research linked to Calcific aortic valve stenosis. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Calcific aortic valve stenosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2024 · PMID 38494474 · open access
Questions about rs1016819
What is rs1016819?
rs1016819 is a single position in the genome, in or near the PRRX1 gene. Published research associates it with calcific aortic valve stenosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs1016819 linked to?
On MyGeneLog this position is linked to Aortic Stenosis. The research behind each link, and its sources, are set out on that condition page.
Does having rs1016819 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1016819 come from?
GWAS Catalog, Nature communications 2024, PMID:38494474. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1012223Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI2Microsoft · Copilot2Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others3Total10Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.