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Cerebrospinal fluid 2'-deoxyuridine levels

RRM1 · rs1015998

What the study found

Who was studied 2,602 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0241 lower (95% confidence interval 0.017-0.031); p = 7 × 10−12.

Where it sits Chromosome 11, band 11p15.4 — in an intron of RRM1.

What each result means

A/A Two copies of the version the research linked to Cerebrospinal fluid 2'-deoxyuridine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Cerebrospinal fluid 2'-deoxyuridine levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Cerebrospinal fluid 2'-deoxyuridine levels. This is the starting point the study compared everyone against.
Source

Questions about rs1015998

What is rs1015998?

rs1015998 is a single position in the genome, in or near the RRM1 gene. Published research associates it with cerebrospinal fluid 2'-deoxyuridine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs1015998 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1015998 come from?

GWAS Catalog, Nature genetics 2024, PMID:39528826. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Cerebrospinal fluid 2'-deoxyuridine levels (rs1015998). MyGeneLog™. https://www.mygenelog.com/variants/rs1015998

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