Standard
Morning vs. evening chronotype
APH1A · rs10157197
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Morning vs. evening chronotype compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Morning vs. evening chronotype.
G/G
Published research associates this genotype with typical/baseline likelihood of Morning vs. evening chronotype — no copies of the reported risk allele.
Source
Genome-wide association analysis identifies novel loci for chronotype in 100,420 individuals from the UK Biobank
Lane JM,
Vlasac I,
Anderson SG,
Kyle SD,
Dixon WG,
Bechtold DA,
Gill S,
Little MA,
Luik A,
Loudon A,
Emsley R,
Scheer FA
and 6 more — show all
Nature communications · 2016 · PMID 26955885 · open access
Questions about rs10157197
What is rs10157197?
rs10157197 is a single position in the genome, in or near the APH1A gene. Published research associates it with morning vs. evening chronotype. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10157197 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10157197 come from?
GWAS Catalog, Nat Commun 2016, PMID:26955885. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants