Sensitive

Prostate cancer

TET2 · rs1015521

Where this position leads

Condition: Prostate Cancer

rs1015521 Condition: Prostate Cancer Prostate Cancer Condition rs1015521 rs1015521 TET2

What the study found

Who was studied 7,822 European ancestry cases, 144,172 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.133 lower (95% confidence interval 0.097-0.169); p = 3 × 10−13.

Where it sits Chromosome 4, band 4q24 — in an intron of TET2.

What each result means

G/G No copy of the version the research linked to Prostate cancer. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Prostate cancer. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Prostate cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs1015521

What is rs1015521?

rs1015521 is a single position in the genome, in or near the TET2 gene. Published research associates it with prostate cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1015521 linked to?

On MyGeneLog this position is linked to Prostate Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs1015521 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1015521 come from?

GWAS Catalog, Scientific reports 2024, PMID:38538606. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Prostate cancer (rs1015521). MyGeneLog™. https://www.mygenelog.com/variants/rs1015521

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