Sensitive

Schizophrenia (MTAG)

BCL11B · rs10150710

Where this position leads

Condition: Schizophrenia

rs10150710 Condition: Schizophrenia Schizophrenia Condition rs10150710 rs10150710 BCL11B

What the study found

Who was studied at least 33,640 European ancestry cases, at least 43,456 European ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0628 higher (95% confidence interval 0.041-0.085); p = 3 × 10−8.

How common The T allele had a frequency of about 44% in the people studied.

Where it sits Chromosome 14, band 14q32.2 — in an intron of BCL11B.

What each result means

C/C No copy of the version the research linked to Schizophrenia (MTAG). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Schizophrenia (MTAG). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Schizophrenia (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10150710

What is rs10150710?

rs10150710 is a single position in the genome, in or near the BCL11B gene. Published research associates it with schizophrenia (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10150710 linked to?

On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.

Does having rs10150710 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10150710 come from?

GWAS Catalog, Translational psychiatry 2021, PMID:33479212. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Schizophrenia (MTAG) (rs10150710). MyGeneLog™. https://www.mygenelog.com/variants/rs10150710

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