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Hip bone size

TMEM260 · rs10149699

What the study found

Who was studied 3,267 European ancestry individuals, 1,619 Chinese ancestry individuals, 843 African American individuals, 446 Hispanic individuals.

The effect Each copy of the G allele shifted the measure 0.11 higher (95% confidence interval 0.071-0.149); p = 1 × 10−9.

Where it sits Chromosome 14, band 14q22.3 — in an intron of TMEM260.

What each result means

A/A No copy of the version the research linked to Hip bone size. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Hip bone size. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Hip bone size. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10149699

What is rs10149699?

rs10149699 is a single position in the genome, in or near the TMEM260 gene. Published research associates it with hip bone size. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10149699 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10149699 come from?

GWAS Catalog, Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA 2020, PMID:32314116. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hip bone size (rs10149699). MyGeneLog™. https://www.mygenelog.com/variants/rs10149699

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