Standard

Creatinine levels

TESHL · rs1014680

Where this position leads

Condition: Kidney Function

rs1014680 Condition: Kidney Function Kidney Function Condition rs1014680 rs1014680 TESHL

What the study found

Who was studied 84,794 Caucasian ancestry individuals.

The effect Each copy of the A allele shifted the measure 7.69 (zscore) higher; p = 1 × 10−14.

How common The A allele had a frequency of about 58% in the people studied.

Where it sits Chromosome 2, band 2q35 — in an intron of TESHL.

What each result means

A/A Two copies of the version the research linked to Creatinine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Creatinine levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Creatinine levels. This is the starting point the study compared everyone against.
Source

Questions about rs1014680

What is rs1014680?

rs1014680 is a single position in the genome, in or near the TESHL gene. Published research associates it with creatinine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs1014680 linked to?

On MyGeneLog this position is linked to Kidney Function. The research behind each link, and its sources, are set out on that condition page.

Does having rs1014680 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs1014680 come from?

GWAS Catalog, Nature genetics 2021, PMID:33414548. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Creatinine levels (rs1014680). MyGeneLog™. https://www.mygenelog.com/variants/rs1014680

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