Standard

Hidradenitis suppurativa

ATL1 · rs10146136

Where this position leads

Condition: Hidradenitis Suppurativa

rs10146136 Condition: Hidradenitis Suppurativa Hidradenitis Suppurativa Condition rs10146136 rs10146136 ATL1

What the study found

Who was studied 3,322 European, Hispanic or Latin American, Asian or unknown ancestry cases, 1,132,141 European, Hispanic or Latin American, Asian or unknown ancestry controls.

The effect The reported allele is A; the catalogue records no effect size ; p = 2 × 10−8.

How common The A allele had a frequency of about 13% in the people studied.

Where it sits Chromosome 14, band 14q22.1 — in an intron of ATL1.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Hidradenitis suppurativa compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Hidradenitis suppurativa.
G/G Published research associates this genotype with typical/baseline likelihood of Hidradenitis suppurativa — no copies of the reported risk allele.
Source

Questions about rs10146136

What is rs10146136?

rs10146136 is a single position in the genome, in or near the ATL1 gene. Published research associates it with hidradenitis suppurativa. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10146136 linked to?

On MyGeneLog this position is linked to Hidradenitis Suppurativa. The research behind each link, and its sources, are set out on that condition page.

Does having rs10146136 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10146136 come from?

GWAS Catalog, The British journal of dermatology 2025, PMID:40650879. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hidradenitis suppurativa (rs10146136). MyGeneLog™. https://www.mygenelog.com/variants/rs10146136

← See all variants