Standard
Serum protein levels (sST2)
SLC9A4 · rs1014286
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Serum protein levels (sST2) — no copies of the reported risk allele. (GWAS Catalog, J Clin Invest 2013, PMID:23999434)
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Serum protein levels (sST2). (GWAS Catalog, J Clin Invest 2013, PMID:23999434)
G/G
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Serum protein levels (sST2) compared to the general population. (GWAS Catalog, J Clin Invest 2013, PMID:23999434)
Source
Common genetic variation at the IL1RL1 locus regulates IL-33/ST2 signaling
Ho JE,
Chen WY,
Chen MH,
Larson MG,
McCabe EL,
Cheng S,
Ghorbani A,
Coglianese E,
Emilsson V,
Johnson AD,
Walter S,
Franceschini N
and 12 more — show all
O'Donnell CJ,
Dehghan A,
Lu C,
Levy D,
Newton-Cheh C,
Lin H,
Felix JF,
Schreiter ER,
Vasan RS,
Januzzi JL,
Lee RT,
Wang TJ
The Journal of clinical investigation · 2013 · PMID 23999434
Questions about rs1014286
What is rs1014286?
rs1014286 is a single position in the genome, in or near the SLC9A4 gene. Published research associates it with serum protein levels (sst2). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs1014286 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs1014286 come from?
GWAS Catalog, J Clin Invest 2013, PMID:23999434. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants