Standard

IgG levels

IGHG1 · rs10136766

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of IgG levels compared to the general population.

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with IgG levels.

G/G Published research associates this genotype with typical/baseline likelihood of IgG levels — no copies of the reported risk allele.

Source

Genetic variants in the immunoglobulin heavy chain locus are associated with the IgG index in multiple sclerosis

Buck D, Albrecht E, Aslam M, Goris A, Hauenstein N, Jochim A, Cepok S, Grummel V, Dubois B, Berthele A, Lichtner P, Gieger C

and 2 more — show all

Winkelmann J, Hemmer B

International Multiple Sclerosis Genetics Consortium · Wellcome Trust Case Control Consortium

Annals of neurology · 2013 · PMID 23225573

Questions about rs10136766

What is rs10136766?

rs10136766 is a single position in the genome, in or near the IGHG1 gene. Published research associates it with igg levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10136766 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10136766 come from?

GWAS Catalog, Ann Neurol 2012, PMID:23225573. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

← See all variants