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Eosinophil count

near EIF5-DT · rs10135205

What the study found

Who was studied 408,112 British individuals.

The effect Each copy of the G allele shifted the measure 0.0149 lower (95% confidence interval 0.011-0.019); p = 3 × 10−11.

How common The G allele had a frequency of about 45% in the people studied.

Where it sits Chromosome 14, band 14q32.32 — between genes, 15.2 kb from EIF5-DT.

What each result means

A/A No copy of the version the research linked to Eosinophil count. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Eosinophil count. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Eosinophil count. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10135205

What is rs10135205?

rs10135205 is a single position in the genome, in or near the near EIF5-DT gene. Published research associates it with eosinophil count. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10135205 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10135205 come from?

GWAS Catalog, Cell 2020, PMID:32888494. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Eosinophil count (rs10135205). MyGeneLog™. https://www.mygenelog.com/variants/rs10135205

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