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Allergen component sensitization (Ambrosia artemisiifolia 1)

near IGHVII-62-1 · rs10129888

What the study found

Who was studied 66 Japanese ancestry pediatric cases, 498 Japanese ancestry pediatric controls.

The effect Each copy of the G allele carried 4.03 times the odds of Allergen component sensitization (Ambrosia artemisiifolia 1) (95% confidence interval 2.483-6.527); p = 2 × 10−8.

How common The G allele had a frequency of about 11% in the people studied.

Where it sits Chromosome 14, band 14q32.33 — between genes, 3.1 kb from IGHVII-62-1.

What each result means

C/C No copy of the version the research linked to Allergen component sensitization (Ambrosia artemisiifolia 1). This is the starting point the study compared everyone against.
C/G One copy of the version the research linked to Allergen component sensitization (Ambrosia artemisiifolia 1). That is a smaller link than two copies.
G/G Two copies of the version the research linked to Allergen component sensitization (Ambrosia artemisiifolia 1). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10129888

What is rs10129888?

rs10129888 is a single position in the genome, in or near the near IGHVII-62-1 gene. Published research associates it with allergen component sensitization (ambrosia artemisiifolia 1). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10129888 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10129888 come from?

GWAS Catalog, The journal of allergy and clinical immunology. Global 2023, PMID:37780799. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Allergen component sensitization (Ambrosia artemisiifolia 1) (rs10129888). MyGeneLog™. https://www.mygenelog.com/variants/rs10129888

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