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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 60,225 Chinese ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.113 lower (95% confidence interval 0.074-0.152); p = 2 × 10−8.
How common The C allele had a frequency of about 13% in the people studied.
Where it sits Chromosome 14, band 14q24.1 — in an intron of RAD51B.
What each result means
C/CTwo copies of the version the research linked to Thyroid peroxidase antibody levels in pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Thyroid peroxidase antibody levels in pregnancy. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Thyroid peroxidase antibody levels in pregnancy. This is the starting point the study compared everyone against.
Nature communications · 2024 · PMID 39266554 · open access
Questions about rs10129646
What is rs10129646?
rs10129646 is a single position in the genome, in or near the RAD51B gene. Published research associates it with thyroid peroxidase antibody levels in pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10129646 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10129646 come from?
GWAS Catalog, Nature communications 2024, PMID:39266554. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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Thyroid peroxidase antibody levels in pregnancy (rs10129646). MyGeneLog™. https://www.mygenelog.com/variants/rs10129646