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Carotid intima media thickness (mean)

near SMILR · rs10110725

What the study found

Who was studied 43,775 European ancestry individuals, 612 Asian ancestry individuals, 291 Black individuals, 215 Mixed ancestry individuals, 292 individuals.

The effect Each copy of the T allele shifted the measure 0.037 higher (95% confidence interval 0.025-0.049); p = 6 × 10−10.

How common The T allele had a frequency of about 54% in the people studied.

Where it sits Chromosome 8, band 8q24.13 — between genes, 11.5 kb from SMILR.

What each result means

A/A No copy of the version the research linked to Carotid intima media thickness (mean). This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Carotid intima media thickness (mean). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Carotid intima media thickness (mean). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10110725

What is rs10110725?

rs10110725 is a single position in the genome, in or near the near SMILR gene. Published research associates it with carotid intima media thickness (mean). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10110725 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10110725 come from?

GWAS Catalog, Arteriosclerosis, thrombosis, and vascular biology 2022, PMID:34852643. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Carotid intima media thickness (mean) (rs10110725). MyGeneLog™. https://www.mygenelog.com/variants/rs10110725

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