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Triglycerides

LPL · rs10105606

Where this position leads

Condition: High Triglycerides

rs10105606 Condition: High Triglycerides High Triglycerides Condition rs10105606 rs10105606 LPL

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Triglycerides — no copies of the reported risk allele. (GWAS Catalog, Arterioscler Thromb Vasc Biol 2010, PMID:20864672)
A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Triglycerides. (GWAS Catalog, Arterioscler Thromb Vasc Biol 2010, PMID:20864672)
C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Triglycerides compared to the general population. (GWAS Catalog, Arterioscler Thromb Vasc Biol 2010, PMID:20864672)
Source
Genetic variants influencing circulating lipid levels and risk of coronary artery disease
Waterworth DM, Ricketts SL, Song K, Chen L, Zhao JH, Ripatti S, Aulchenko YS, Zhang W, Yuan X, Lim N, Luan J, Ashford S
and 54 more — show all
Wheeler E, Young EH, Hadley D, Thompson JR, Braund PS, Johnson T, Struchalin M, Surakka I, Luben R, Khaw KT, Rodwell SA, Loos RJ, Boekholdt SM, Inouye M, Deloukas P, Elliott P, Schlessinger D, Sanna S, Scuteri A, Jackson A, Mohlke KL, Tuomilehto J, Roberts R, Stewart A, Kesäniemi YA, Mahley RW, Grundy SM, McArdle W, Cardon L, Waeber G, Vollenweider P, Chambers JC, Boehnke M, Abecasis GR, Salomaa V, Järvelin MR, Ruokonen A, Barroso I, Epstein SE, Hakonarson HH, Rader DJ, Reilly MP, Witteman JC, Hall AS, Samani NJ, Strachan DP, Barter P, van Duijn CM, Kooner JS, Peltonen L, Wareham NJ, McPherson R, Mooser V, Sandhu MS
Wellcome Trust Case Control Consortium
Arteriosclerosis, thrombosis, and vascular biology · 2010 · PMID 20864672

Questions about rs10105606

What is rs10105606?

rs10105606 is a single position in the genome, in or near the LPL gene. Published research associates it with triglycerides. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10105606 linked to?

On MyGeneLog this position is linked to High Triglycerides. The research behind each link, and its sources, are set out on that condition page.

Does having rs10105606 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10105606 come from?

GWAS Catalog, Arterioscler Thromb Vasc Biol 2010, PMID:20864672. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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