Post-traumatic stress disorder (mental health questionnaire or predicted)
near BIN3 · rs10105545
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 497,803 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.013 lower (95% confidence interval 0.0089-0.0171); p = 5 × 10−10.
Where it sits Chromosome 8, band 8p21.3 — between genes, 7.6 kb from BIN3.
What each result means
A/ATwo copies of the version the research linked to Post-traumatic stress disorder (mental health questionnaire or predicted). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Post-traumatic stress disorder (mental health questionnaire or predicted). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Post-traumatic stress disorder (mental health questionnaire or predicted). This is the starting point the study compared everyone against.
Molecular psychiatry · 2022 · PMID 35181757 · open access
Questions about rs10105545
What is rs10105545?
rs10105545 is a single position in the genome, in or near the near BIN3 gene. Published research associates it with post-traumatic stress disorder (mental health questionnaire or predicted). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10105545 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10105545 come from?
GWAS Catalog, Molecular psychiatry 2022, PMID:35181757. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
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Post-traumatic stress disorder (mental health questionnaire or predicted) (rs10105545). MyGeneLog™. https://www.mygenelog.com/variants/rs10105545