Standard

Response to statin therapy

LOC646909 · rs10091038

Where this position leads

Condition: Cholesterol (LDL, HDL and Total)

rs10091038 Condition: Cholesterol (LDL, HDL and Total) Cholesterol (LDL, HDL and Total) Condition rs10091038 rs10091038 LOC646909

What the study found

Who was studied 3,928 European ancestry individuals.

The effect The reported allele is A; the catalogue records no effect size ; p = 3 × 10−8.

How common The A allele had a frequency of about 43% in the people studied.

Where it sits Chromosome 8, band 8p12 — in an intron of LINC02948.

What each result means

A/A Two copies of the version the research linked to Response to statin therapy. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/C One copy of the version the research linked to Response to statin therapy. That is a smaller link than two copies.
C/C No copy of the version the research linked to Response to statin therapy. This is the starting point the study compared everyone against.
Source

Questions about rs10091038

What is rs10091038?

rs10091038 is a single position in the genome, in or near the LOC646909 gene. Published research associates it with response to statin therapy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10091038 linked to?

On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.

Does having rs10091038 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10091038 come from?

GWAS Catalog, PLoS One 2010, PMID:20339536. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Response to statin therapy (rs10091038). MyGeneLog™. https://www.mygenelog.com/variants/rs10091038

← See all variants