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Response to statin therapy

LOC646909 · rs10091038

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Response to statin therapy compared to the general population. (GWAS Catalog, PLoS One 2010, PMID:20339536)
A/C Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Response to statin therapy. (GWAS Catalog, PLoS One 2010, PMID:20339536)
C/C Published research associates this genotype with typical/baseline likelihood of Response to statin therapy — no copies of the reported risk allele. (GWAS Catalog, PLoS One 2010, PMID:20339536)

Source: GWAS Catalog, PLoS One 2010, PMID:20339536

Questions about rs10091038

What is rs10091038?

rs10091038 is a single position in the genome, in or near the LOC646909 gene. Published research associates it with response to statin therapy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs10091038 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10091038 come from?

GWAS Catalog, PLoS One 2010, PMID:20339536. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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