Standard

systolic blood pressure (SBP, mean, inv-normal transformed)

XKR6 · rs10088408

Where this position leads

Condition: Blood Pressure

rs10088408 Condition: Blood Pressure Blood Pressure Condition rs10088408 rs10088408 XKR6

What the study found

Who was studied 119,331 African American or Afro-Caribbean individuals, 57,988 Hispanic or Latin American individuals, 6,420 East Asian ancestry individuals, 425,740 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0259 higher (95% confidence interval 0.019-0.033); p = 4 × 10−12.

How common The C allele had a frequency of about 45% in the people studied.

Where it sits Chromosome 8, band 8p23.1 — in an intron of XKR6.

What each result means

C/C Two copies of the version the research linked to systolic blood pressure (SBP, mean, inv-normal transformed). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to systolic blood pressure (SBP, mean, inv-normal transformed). That is a smaller link than two copies.
T/T No copy of the version the research linked to systolic blood pressure (SBP, mean, inv-normal transformed). This is the starting point the study compared everyone against.
Source

Questions about rs10088408

What is rs10088408?

rs10088408 is a single position in the genome, in or near the XKR6 gene. Published research associates it with systolic blood pressure (sbp, mean, inv-normal transformed). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10088408 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs10088408 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10088408 come from?

GWAS Catalog, Science (New York, N.Y.) 2024, PMID:39024449. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

systolic blood pressure (SBP, mean, inv-normal transformed) (rs10088408). MyGeneLog™. https://www.mygenelog.com/variants/rs10088408

← See all variants