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General factor of neuroticism

XKR6 · rs10087081

Where this position leads

Condition: Neuroticism

rs10087081 Condition: Neuroticism Neuroticism Condition rs10087081 rs10087081 XKR6

What the study found

Who was studied 270,059 British ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0132 higher (95% confidence interval 0.0098-0.0166); p = 5 × 10−14.

Where it sits Chromosome 8, band 8p23.1 — in an intron of XKR6.

What each result means

C/C Two copies of the version the research linked to General factor of neuroticism. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to General factor of neuroticism. That is a smaller link than two copies.
T/T No copy of the version the research linked to General factor of neuroticism. This is the starting point the study compared everyone against.
Source

Questions about rs10087081

What is rs10087081?

rs10087081 is a single position in the genome, in or near the XKR6 gene. Published research associates it with general factor of neuroticism. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10087081 linked to?

On MyGeneLog this position is linked to Neuroticism. The research behind each link, and its sources, are set out on that condition page.

Does having rs10087081 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10087081 come from?

GWAS Catalog, Molecular psychiatry 2020, PMID:30867560. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

General factor of neuroticism (rs10087081). MyGeneLog™. https://www.mygenelog.com/variants/rs10087081

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