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Height

SMIM29 · rs10080749

Where this position leads

Condition: Height

rs10080749 Condition: Height Height Condition rs10080749 rs10080749 SMIM29

What the study found

Who was studied 2,603 Korean ancestry males, 2,869 Korean ancestry females; replicated in 19,571 Korean ancestry males, 37,321 Korean ancestry females.

The effect Each copy of the G allele shifted the measure 0.41 higher (95% confidence interval 0.31-0.51); p = 1 × 10−18.

How common The G allele had a frequency of about 17% in the people studied.

Where it sits Chromosome 6, band 6p21.31 — in an intron of SMIM29-AS1.

What each result means

A/A No copy of the version the research linked to Height. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Height. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Height. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs10080749

What is rs10080749?

rs10080749 is a single position in the genome, in or near the SMIM29 gene. Published research associates it with height. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs10080749 linked to?

On MyGeneLog this position is linked to Height. The research behind each link, and its sources, are set out on that condition page.

Does having rs10080749 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs10080749 come from?

GWAS Catalog, Frontiers in genetics 2021, PMID:34054925. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Height (rs10080749). MyGeneLog™. https://www.mygenelog.com/variants/rs10080749

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