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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 13,358 European ancestry cases, 43,071 European ancestry controls; replicated in 24,099 cases, 1,484,025 controls.
The effect
Each copy of the A allele shifted the measure 0.094 lower; p = 1 × 10−9.
How common The A allele had a frequency of about 62% in the people studied.
Where it sits Chromosome 5, band 5p15.33 — in an intron of CEP72-DT.
What each result means
A/ATwo copies of the version the research linked to Barrett's esophagus. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Barrett's esophagus. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Barrett's esophagus. This is the starting point the study compared everyone against.
rs10080150 is a single position in the genome, in or near the CEP72-DT gene. Published research associates it with barrett's esophagus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10080150 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10080150 come from?
GWAS Catalog, Gut 2022, PMID:34187846. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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