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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 4,702 Admixed Latin American ancestry cases, 68,573 Admixed Latin American ancestry controls, European, African, East Asian, South Asian or Admixed American individuals (See The COVID-19 Host Genetics Initiative, v7 ALL B2).
The effect
Each copy of the T allele shifted the measure 0.0744 lower (95% confidence interval 0.052-0.097); p = 1 × 10−10.
Where it sits Chromosome 5, band 5q31.1 — in an intron of CARINH.
What each result means
C/CNo copy of the version the research linked to COVID-19 (hospitalized covid vs population). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to COVID-19 (hospitalized covid vs population). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to COVID-19 (hospitalized covid vs population). That is the strongest link of the three results. A link in a study is not a diagnosis.
rs10066378 is a single position in the genome, in or near the CARINH gene. Published research associates it with covid-19 (hospitalized covid vs population). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs10066378 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs10066378 come from?
GWAS Catalog, eLife 2024, PMID:39361370. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
COVID-19 (hospitalized covid vs population) (rs10066378). MyGeneLog™. https://www.mygenelog.com/variants/rs10066378